Dr. Keith L. Black

1957

Neurosurgeon, Cancer Researcher

Dr. Black has pioneered research on designing ways to open the blood-brain barrier, enabling chemotherapeutic drugs to be delivered directly into the tumor. His other ground-breaking research includes developing a vaccine to enhance the body’s immune response to brain tumors, using gene arrays to develop molecular profiles of tumors, employing optical technology for brain mapping, and using focused microwave energy to noninvasively destroy brain tumors.

Dr. Black is a renowned neurosurgeon and scientist who is the chairman of the Department of Neurosurgery and the director of the Maxine Dunitz Neurosurgical Institute at Cedars-Sinai Medical Center. Dr. Black also holds the Ruth and Lawrence Harvey Chair in Neurosciences and is a professor of neurosurgery at Cedars-Sinai Medical Center. At age seventeen, he published his first scientific paper, which earned the Westinghouse Science Award. He completed an accelerated college program at the University of Michigan and earned both his undergraduate and medical degrees in six years. Dr. Black completed his internship in general surgery and residency in neurological surgery at the University of Michigan Medical Center in Ann Arbor.

After serving his internship and residency at the University of Michigan, in 1987 he moved to the UCLA Medical Center in Los Angeles where he later became head of UCLA’s Comprehensive Brain Tumor Program. In 1997, after 10 years at UCLA, he moved to Cedars-Sinai Medical Center to head the Maxine Dunitz Neurosurgical Institute. He was also on the faculty of the University of California, Irvine School of Medicine from 1998 to 2003. In 2007 he opened the new Johnnie L. Cochran Jr. Brain Tumor Center at Cedars-Sinai, a research center named after the famous lawyer who had been Black’s patient and supporter.

Black has been a frequent subject of media reports on medical advances in neurosurgery. He was featured in a 1996 episode of the PBS program The New Explorers entitled “Outsmarting the Brain”.Esquire included him in its November 1999 “Genius Issue” as one of the “21 Most Important People of the 21st Century.” He has been cited as an expert in reports about whether mobile phone use affects the incidence of brain tumors.

He is also noted for his very busy surgery schedule: a 2004 Discover article noted that he performs about 250 brain surgeries per year and that at age 46 he had “already performed more than 4,000 brain surgeries, the medical equivalent of closing in on baseball’s all-time career hits record.” (As of 2009, Black’s surgery count had risen to “more than 5,000 operations for resection of brain tumors”.

In 1997, Time magazine featured Black on the cover of a special edition called “Heroes of Medicine”.The accompanying article described Black’s reputation as a surgeon who would operate on tumors that other doctors would not, as well as aspects of his medical research, including his discovery that the peptide bradykinin can be effective in opening the blood–brain barrier.

In 2009 Black published his autobiography, co-authored with Arnold Mann, entitled Brain Surgeon New York Times reviewer Abigail Zuger described the book as a “fascinating, if somewhat stilted, memoir”. The Publishers Weekly review commented that the book “examines racial hurdles he had to leap to become a neurosurgeon” and “alternate incisive writing about incisions with his personal memoir, insightful and inspirational.